I have a plan for moving the ASP media db that we use for logging the tapes, LPs and so forth that we store. I have this plan because I intend to bring the current host down and turn it in to an aquarium or something.
Here's the plan:
Run IIS on the editor's machine and restrict access via NTLM. To do this I need to edit a few ASP pages to point to the mdb file and set permission on the directory containing all the code to the windows user running the physical machine. IIS gets set up to use "Windows Authentication" for access. This will stop anyone but a local user (on the physical machine) from accessing the site; I have also put in a request to lock the machine down as tight as can be.

I have implemented the general plan in a VM and it seems to work well.